Chapman L J, Sauter S L, Henning R A, Dodson V N, Reddan W G, Matthews C G
Department of Neurology, University of Wisconsin, Madison.
Br J Ind Med. 1990 Dec;47(12):838-43. doi: 10.1136/oem.47.12.838.
Tremor was measured from the index finger during low force, position holding in 18 control subjects and 18 battery workers with low level exposure to mercury. All workers were asymptomatic on clinical neurological examination. No differences were found in average tremor amplitudes between the groups, but statistically significant abnormalities in tremor frequency distribution existed. Tremor power spectra in the group of mercury workers were shifted toward the higher frequencies and compressed into narrow frequency peaks. These results suggest that measurements of finger tremor that evaluate the frequency distribution can produce a higher diagnostic yield than traditional visual clinical judgement. The findings also confirm other reports that currently permitted exposures to mercury are associated with subtle but distinctive differences in tremor accompanying voluntary movement.
在18名对照受试者和18名低水平汞暴露的电池厂工人保持低强度姿势时，测量其食指的震颤情况。所有工人在临床神经学检查中均无症状。两组之间的平均震颤幅度没有差异，但在震颤频率分布上存在具有统计学意义的异常。汞作业工人组的震颤功率谱向高频方向移动，并压缩成狭窄的频率峰值。这些结果表明，评估频率分布的手指震颤测量方法比传统的视觉临床判断能产生更高的诊断率。研究结果还证实了其他报告，即目前允许的汞暴露与伴随自主运动的震颤中细微但独特的差异有关。
