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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Thabrew M I, Olorunsogo O O, Olowookere J O, Bababunmi E A

Xenobiotica. 1982 Dec;12(12):849-53. doi: 10.3109/00498258209038956.

[14C]Benzoic acid administered to rats fed a normal diet was excreted mainly (99% of 24h excretion) as hippuric acid. 2. In protein-energy malnourished rats, only about 74% of [14C]benzoic acid administered was excreted as hippuric acid. The remainder was excreted as the glucuronide conjugate. 3. The oxidative phosphorylation capacity of liver mitochondria of malnourished rats was 30% less than that of normal rat liver mitochondria. 4. The decreased rate in oxidative phosphorylation is discussed in relationship to the observed decrease in glycine conjugation.

给正常饮食的大鼠投喂[14C]苯甲酸后，其主要以马尿酸形式排出（占24小时排泄量的99%）。2. 在蛋白质-能量营养不良的大鼠中，所投喂的[14C]苯甲酸仅有约74%以马尿酸形式排出。其余部分则以葡萄糖醛酸苷结合物形式排出。3. 营养不良大鼠肝脏线粒体的氧化磷酸化能力比正常大鼠肝脏线粒体低30%。4. 结合观察到的甘氨酸结合作用降低的情况，对氧化磷酸化速率降低进行了讨论。

Thabrew M I, Olorunsogo O O, Olowookere J O, Bababunmi E A

Xenobiotica. 1982 Dec;12(12):849-53. doi: 10.3109/00498258209038956.

[14C]Benzoic acid administered to rats fed a normal diet was excreted mainly (99% of 24h excretion) as hippuric acid. 2. In protein-energy malnourished rats, only about 74% of [14C]benzoic acid administered was excreted as hippuric acid. The remainder was excreted as the glucuronide conjugate. 3. The oxidative phosphorylation capacity of liver mitochondria of malnourished rats was 30% less than that of normal rat liver mitochondria. 4. The decreased rate in oxidative phosphorylation is discussed in relationship to the observed decrease in glycine conjugation.

给正常饮食的大鼠投喂[14C]苯甲酸后，其主要以马尿酸形式排出（占24小时排泄量的99%）。2. 在蛋白质-能量营养不良的大鼠中，所投喂的[14C]苯甲酸仅有约74%以马尿酸形式排出。其余部分则以葡萄糖醛酸苷结合物形式排出。3. 营养不良大鼠肝脏线粒体的氧化磷酸化能力比正常大鼠肝脏线粒体低30%。4. 结合观察到的甘氨酸结合作用降低的情况，对氧化磷酸化速率降低进行了讨论。