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[恶性纵隔胚胎瘤。一例伴有肺转移。化疗后完全缓解]

[Malignant mediastinal embryoma. A case with pulmonary metastasis. Complete remission after chemotherapy].

作者信息

Allard P, Kermarec J, Epardeau B, Schwartz J, Natali F, Haguenauer G

出版信息

Ann Med Interne (Paris). 1982;133(8):597-9.

PMID:7171189
Abstract

Rapid increase in growth of a pulmonary metastasis following incomplete excision of a malignant mediastinal embryoma was treated by multiple chemotherapy combining platinum derivatives, actinomycin B, bleomycin, and vincaleucoblastin. Complete remission was obtained. These extremely rare tumours have a histological appearance close to that of testicular tumours. Until recently, their prognosis was such that therapy appeared to be of no avail, but this has been modified by new chemotherapy schedules including, more particularly, the use of platinum.

摘要

恶性纵隔胚胎瘤不完全切除后肺转移灶迅速生长,采用铂类衍生物、放线菌素B、博来霉素和长春碱联合多种化疗进行治疗,获得了完全缓解。这些极其罕见的肿瘤组织学表现与睾丸肿瘤相近。直到最近,其预后一直很差,治疗似乎无效,但新的化疗方案,尤其是铂类药物的使用,改变了这种情况。

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