Gough D A
Diabetes Care. 1982 May-Jun;5(3):266-70. doi: 10.2337/diacare.5.3.266.
The concentration of over 20 biochemicals in bovine aqueous humor was determined by conventional means, and the contribution of each to the observed optical rotation was estimated. Of those studied, only glucose and the total proteins made a significant contribution. However, other unidentified chemicals apparently also contribute to the optical activity since it was not possible to reconstruct the actual aqueous humor optical rotation based on the chemicals included. Alternative experimental approaches that may yield more complete results are discussed. With further work, optical rotation might be used as the basis of a noninvasive sensor for measuring the glucose concentration of aqueous humor in the intact eye.
通过传统方法测定了牛房水中20多种生化物质的浓度,并估算了每种物质对观察到的旋光度的贡献。在这些研究的物质中,只有葡萄糖和总蛋白有显著贡献。然而,其他未鉴定的化学物质显然也对旋光性有贡献,因为根据所包含的化学物质无法重建实际的房水旋光度。讨论了可能产生更完整结果的替代实验方法。随着进一步的研究,旋光度可能会作为一种无创传感器的基础,用于测量完整眼睛中房水的葡萄糖浓度。