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与药物相关的急性医疗入院情况。

Drug-related acute medical admissions.

作者信息

Ramsay L E, Freestone S, Silas J H

出版信息

Hum Toxicol. 1982 Oct;1(4):379-86. doi: 10.1177/096032718200100403.

Abstract

1 A survey of urgent admissions to a general medical unit in Sheffield in 1978 showed that about 25% of admissions were caused by drug-related illness; 18% by self-poisoning, 3.1% by definite or probable adverse reactions, 3.1% by possible adverse reactions, and 1.4% by non-compliance with drug treatment. These patients accounted for 10.8% of the bed use by patients admitted urgently. 2 Drug-related admissions to the unit did not increase between 1974 and 1980. 3 The use of barbiturates for self-poisoning declined sharply, while that of paracetamol increased steadily. Self-poisoning with dextropropoxyphene appeared to peak in 1978, and then decline. 4 While drug-related illness caused the admission of 81% of all patients under the age of 30 years, they rarely came to harm. Self-poisoning had a high mortality in older patients, and they were also the principal sufferers from adverse drug reactions.

摘要
  1. 一项对1978年谢菲尔德一家普通内科病房紧急入院情况的调查显示,约25%的入院病例是由药物相关疾病导致的;其中18%是由于自我中毒,3.1%是由明确或可能的不良反应引起,3.1%是由可能的不良反应引起,1.4%是由于不遵守药物治疗。这些患者占紧急入院患者床位使用的10.8%。2. 该病房1974年至1980年间与药物相关的入院病例没有增加。3. 用于自我中毒的巴比妥类药物使用量急剧下降,而对乙酰氨基酚的使用量则稳步上升。右丙氧芬自我中毒似乎在1978年达到峰值,然后下降。4. 虽然药物相关疾病导致30岁以下所有患者中有81%入院,但他们很少受到伤害。自我中毒在老年患者中死亡率很高,而且他们也是药物不良反应的主要受害者。

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