Chan T Y, Critchley J A
Department of Clinical Pharmacology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT.
Southeast Asian J Trop Med Public Health. 1994 Sep;25(3):579-82.
To study the pattern of acute poisoning in the New Territories East of Hong Kong, 291 adult cases admitted to the Prince of Wales Hospital in 1989 were reviewed. The female-to-male ratio was 2.3 to 1 and the majority of patients (83%) were below the age of 40. The main poisons involved were hypnotics and sedatives (44.3%), household products (14.8%) and analgesics (10%). The poisoning was intentional in the majority of cases (98.6%). A specific antidote was necessary in 5.2% of cases. Four patients died after admission giving an overall mortality of 1.4%. When compared to the findings from other western countries, important variations in the pattern of acute poisoning were seen in Hong Kong. Firstly, a substantial proportion of drugs ingested were not dispensed labeled although their nature could usually be determined. Secondly, "Dettol", a household antiseptic, was commonly used in self-poisoning episodes. The lack of drug identification labeling on dispensed medicines outside hospitals is of great concern to all physicians in Hong Kong.
为研究香港新界东部的急性中毒模式,我们回顾了1989年入住威尔士亲王医院的291例成年中毒病例。男女比例为2.3比1,大多数患者(83%)年龄在40岁以下。主要涉及的毒物为催眠药和镇静剂(44.3%)、家用产品(14.8%)和镇痛药(10%)。大多数中毒病例(98.6%)是故意的。5.2%的病例需要使用特效解毒剂。4例患者入院后死亡,总死亡率为1.4%。与其他西方国家的研究结果相比,香港急性中毒模式存在重要差异。首先,尽管通常可以确定所摄入药物的性质,但相当一部分药物在配药时没有贴上标签。其次,家用消毒剂“滴露”常用于自我中毒事件。医院外配药缺乏药品标识标签,这引起了香港所有医生的极大关注。