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慢性淋巴细胞白血病中HLA - A、B、C及梅里特B细胞同种抗原特异性的分布

Distribution of HLA-A, B, C and the Merrit B-cell alloantigen specificities in chronic lymphatic leukemia.

作者信息

Gossett T, Walford R, Gatti R M

出版信息

Prog Clin Biol Res. 1977;16:55-63.

PMID:71744
Abstract

Based upon reactions with both normal peripheral B-lymphocytes and a CLL panel, an additional 3 new specificities of the Merritt B-cell alloantigenic system have been defined. this brings the number of provisionally designated specificities to 22. The system of antigenic determinants is well represented on normal B-lymphocytes, and has a roughly similar distribution when compared to the CLL panel; however, evidence is presented which suggests that certain speficities may have significantly idfferent distributions on the 2 different panels, but the number of cells tested is low.

摘要

基于与正常外周B淋巴细胞以及慢性淋巴细胞白血病(CLL)样本的反应,已确定梅里特B细胞同种抗原系统的另外3种新特异性。这使得临时指定的特异性数量达到22种。抗原决定簇系统在正常B淋巴细胞上有很好的表现,与CLL样本相比分布大致相似;然而,有证据表明某些特异性在这两种不同样本上的分布可能有显著差异,但所检测的细胞数量较少。

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