胰液对犬基础胰腺和胃液分泌的影响。
Effect of pancreatic juice on basal pancreatic and gastric secretion in dogs.
作者信息
Magee D F, Naruse S
出版信息
J Physiol. 1982 Sep;330:489-96. doi: 10.1113/jphysiol.1982.sp014354.
Abstract
- The effect of duodenal infusion of pancreatic juice on basal pancreatic and gastric secretion was studied in five conscious dogs provided with pancreatic fistulae, gastric fistulae and Heidenhain fundic pouches. 2. Pancreatic juice and trypsin stimulated a pancreatic secretion rich in protein. 3. Autodigested juice without proteolytic activities also stimulated the secretion. Boiling the juice or addition of trypsin inhibitor to the juice diminished the augmented secretion. 4. It seems, therefore, that trypsin is necessary even in proteolytically inactive autodigested juice for pancreatic stimulation. 5. In dogs, unlike rats and pigs, basal pancreatic secretion is not under negative feed-back control by duodenal tryptic activity. 6. Basal gastric secretion was not significantly changed by duodenal infusion of pancreatic juice.
摘要
- 在五只装有胰瘘、胃瘘和海登海因胃底小囊的清醒犬中，研究了十二指肠注入胰液对基础胰腺和胃分泌的影响。2. 胰液和胰蛋白酶刺激了富含蛋白质的胰腺分泌。3. 无蛋白水解活性的自消化胰液也刺激了分泌。将胰液煮沸或向胰液中添加胰蛋白酶抑制剂可减少增强的分泌。4. 因此，似乎即使在无蛋白水解活性的自消化胰液中，胰蛋白酶对于胰腺刺激也是必需的。5. 在犬中，与大鼠和猪不同，基础胰腺分泌不受十二指肠胰蛋白酶活性的负反馈控制。6. 十二指肠注入胰液对基础胃分泌没有显著影响。
相似文献
1
Effect of pancreatic juice on basal pancreatic and gastric secretion in dogs.胰液对犬基础胰腺和胃液分泌的影响。
J Physiol. 1982 Sep;330:489-96. doi: 10.1113/jphysiol.1982.sp014354.
2
Effects of intestinal amylase and trypsin on pancreatic secretion in the pig.肠道淀粉酶和胰蛋白酶对猪胰腺分泌的影响。
Scand J Gastroenterol. 1979;14(8):1009-13.
3
Effect of pancreatic juice and trypsin on oleic acid-stimulated pancreatic secretion and plasma secretin in dogs.胰液和胰蛋白酶对油酸刺激犬胰腺分泌及血浆促胰液素的影响。
Gastroenterology. 1989 May;96(5 Pt 1):1330-6. doi: 10.1016/s0016-5085(89)80020-4.
4
Action of amino acids on stomach, pancreas, and gallbladder in dogs.
Int J Pancreatol. 1989 Feb;4(1):41-9. doi: 10.1007/BF02924146.
5
Cyclic changes of plasma pancreatic polypeptide and pancreatic secretion in fasting dogs.禁食犬血浆胰多肽和胰腺分泌的周期性变化
J Physiol. 1983 Aug;341:453-61. doi: 10.1113/jphysiol.1983.sp014816.
6
Role of gastric juice in feedback regulation of rat pancreatic secretion by luminal proteases.胃液在管腔蛋白酶对大鼠胰腺分泌的反馈调节中的作用。
Pancreas. 1990 Jul;5(4):445-51. doi: 10.1097/00006676-199007000-00012.
7
Pancreatic and gastric secretion in rats studied by means of duodenal and gastric perfusion.通过十二指肠和胃灌注法对大鼠胰腺和胃分泌的研究。
Scand J Gastroenterol. 1972;7(1):47-53. doi: 10.3109/00365527209180738.
8
Effect of atropine on pancreatic secretion in conscious rats.阿托品对清醒大鼠胰腺分泌的影响。
Digestion. 1986;33(1):17-25. doi: 10.1159/000199270.
9
[Effect of sorbit on bile secretion, secretion of gastric, duodenal and pancreatic juice in norm and in experimental pancreatitis].[山梨醇对正常及实验性胰腺炎状态下胆汁分泌、胃液、十二指肠液及胰液分泌的影响]
Farmakol Toksikol. 1969 Jan-Feb;32(1):75-8.
10
Effects of motilin on gastric and pancreatic secretion in dogs.胃动素对犬胃和胰腺分泌的影响。
Scand J Gastroenterol Suppl. 1976;39:57-61.
引用本文的文献
1
Gastrin-releasing peptide and CCK after intraduodenal inhibition of proteases in dogs.十二指肠内抑制犬蛋白酶后胃泌素释放肽与胆囊收缩素的变化
Int J Pancreatol. 1994 Jun;15(3):209-14. doi: 10.1007/BF02924196.
2
Neural control of periodic secretion of the pancreas and the stomach in fasting dogs.禁食犬胰腺和胃周期性分泌的神经控制
J Physiol. 1983 Nov;344:153-60. doi: 10.1113/jphysiol.1983.sp014930.
3
Cyclic changes of plasma pancreatic polypeptide and pancreatic secretion in fasting dogs.禁食犬血浆胰多肽和胰腺分泌的周期性变化
J Physiol. 1983 Aug;341:453-61. doi: 10.1113/jphysiol.1983.sp014816.
4
Characteristics of secretin-stimulated pancreatic secretion in dogs.犬促胰液素刺激胰腺分泌的特征
J Physiol. 1984 Nov;356:391-9. doi: 10.1113/jphysiol.1984.sp015472.
5
The role of motilin in periodic interdigestive pancreatic secretion in dogs.胃动素在犬周期性消化间期胰腺分泌中的作用。
J Physiol. 1984 Oct;355:441-7. doi: 10.1113/jphysiol.1984.sp015429.
6
Influence of treatment with pancreatic extracts on pancreatic enzyme secretion.胰腺提取物治疗对胰腺酶分泌的影响。
Gut. 1990 Feb;31(2):243. doi: 10.1136/gut.31.2.243.
本文引用的文献
1
THE ESTIMATION OF PEPSIN, TRYPSIN, PAPAIN, AND CATHEPSIN WITH HEMOGLOBIN.用血红蛋白对胃蛋白酶、胰蛋白酶、木瓜蛋白酶和组织蛋白酶的测定
J Gen Physiol. 1938 Sep 20;22(1):79-89. doi: 10.1085/jgp.22.1.79.
2
Effect of excluding pancreatic juice from duodenum on secretory response of pancreas to a meal.将胰液从十二指肠排除对胰腺对进食的分泌反应的影响。
Proc Soc Exp Biol Med. 1951 Jul;77(3):383-5. doi: 10.3181/00379727-77-18785.
3
Mechanism of canine gastric hypersecretion after complete pancreatic ductal obstruction.
Am J Physiol. 1963 Jul;205:89-93. doi: 10.1152/ajplegacy.1963.205.1.89.
4
The effect of pancreatic fistula on gastric secretion.胰瘘对胃液分泌的影响。
Arch Surg. 1959 Dec;79:1004-8. doi: 10.1001/archsurg.1959.04320120146018.
5
Pancreatic influences on gastric secretions.胰腺对胃分泌的影响。
Surgery. 1961 Jul;50:126-33.
6
Down with multiple t-tests.摒弃多重t检验。
Gastroenterology. 1981 Mar;80(3):615-20.
7
8
The role of gastric secretion in post-diverted pancreatic hypersecretion in conscious rats.胃分泌在清醒大鼠旷置术后胰腺高分泌中的作用。
J Physiol. 1982 May;326:453-9. doi: 10.1113/jphysiol.1982.sp014205.
9
Relationship between duodenal pH and pancreatic secretion in dogs and pigs.犬和猪十二指肠pH值与胰腺分泌之间的关系。
Ann Surg. 1967 Nov;166(5):778-82. doi: 10.1097/00000658-196711000-00007.
10
Diversion of pancreatic juice on gastric and pancreatic response to a meal stimulus.
Am J Physiol. 1967 Sep;213(3):637-9. doi: 10.1152/ajplegacy.1967.213.3.637.
Zotero 插件