Kundu S K, Hazra S K, Ghosh S, Chaudhuri S
Lepr India. 1982 Jul;54(3):489-98.
Corticosteroids are known to influence the hypersensitivity reaction in a number of diseases involving hypersensitivity of tissues and alter the antigen antibody reactions in vivo. Corticosteroids administered in thirty tuberculoid cases for a period of 3 weeks showed negative response in the lepromin positive cases uniformly thereby proving suppression of cell mediated immunity in tuberculoid cases under the influence of corticosteroids; hence polar concept of tuberculoid type may be under question with continuous and prolonged corticosteroid therapy under necessity.
已知皮质类固醇会影响许多涉及组织超敏反应的疾病中的超敏反应，并改变体内的抗原抗体反应。对30例结核样型麻风病患者给予皮质类固醇治疗3周，结果显示，所有麻风菌素阳性患者均呈阴性反应，从而证明在皮质类固醇的影响下，结核样型麻风病患者的细胞介导免疫受到抑制；因此，在必要时持续和长期使用皮质类固醇治疗的情况下，结核样型麻风病的两极概念可能会受到质疑。
