McCurdy H H, Solomons E T
J Anal Toxicol. 1982 Sep-Oct;6(5):253-4. doi: 10.1093/jat/6.5.253.
A method is presented for the analysis of ethylene glycol in whole blood by GC/FID using 1,2-butanediol as the internal standard (IS). The diols are derivatized during extraction from whole blood using n-butylboronic acid and then extracted as pseudo weak acids prior to analysis. As little as 10 mg/L of ethylene glycol in blood can be detected by this method.