Taylor D N, Porter B W, Williams C A, Miller H G, Bopp C A, Blake P A
West J Med. 1982 Nov;137(5):365-9.
From April 24 to May 11, 1981, an outbreak of approximately 200 cases of Campylobacter jejuni enteritis occurred in Arizona in persons who drank one brand of unpasteurized milk. Two cohort studies showed that households with members who drank raw milk reported diarrheal illness significantly more frequently than those in which no one drank raw milk (P=.003 and P=.001; relative risk 4.70 and 3.85, respectively). Of 19 serotyped C jejuni organisms isolated from persons who drank raw milk from the implicated dairy, 18 were of a single serotype.C jejuni was not detected in the milk or the milk filters cultured a week after the outbreak, but fecal excretion of Campylobacter of multiple serotypes was higher in the dairy herd that produced the implicated raw milk (48 percent) than in control herds (16 percent).
1981年4月24日至5月11日,亚利桑那州爆发了一起空肠弯曲菌肠炎疫情,约200人患病,这些患者均饮用了某一品牌的未杀菌牛奶。两项队列研究表明,家庭成员饮用生牛奶的家庭报告腹泻疾病的频率显著高于无人饮用生牛奶的家庭(P = 0.003和P = 0.001;相对风险分别为4.70和3.85)。从涉事奶牛场饮用生牛奶的患者中分离出的19株空肠弯曲菌菌株,有18株属于单一血清型。疫情爆发一周后,在牛奶或牛奶过滤器中未检测到空肠弯曲菌,但生产涉事生牛奶的奶牛群中多种血清型弯曲菌的粪便排泄率(48%)高于对照牛群(16%)。