Fontaine R E, Cohen M L, Martin W T, Vernon T M
Am J Epidemiol. 1980 Feb;111(2):247-53. doi: 10.1093/oxfordjournals.aje.a112892.
On August 3, 1976, ongoing Salmonella surveillance in Colorado first detected an epidemic of Salmonella heidelberg infections that eventually totaled 339 isolates. The majority of the cases occurred between July 23 and August 12 in two widely separated cities: Denver and Pueblo. Epidemiologic investigation successively incriminated 1) recent dining at Mexican-style restaurants (p less than 0.001), 2) eating foods containing cheese in these restaurants (p = 0.029), and 3) consumption of cheddar cheese from a single shipment of a single manufacturer (p less than 0.01). The prompt investigation enabled an embargo of 2087 kg (41%) of the contaminated cheese. S. heidelberg was isolated from seven production lots of the incriminated cheese. Surveillance and the epidemiologic investigation may have resulted in prevention of 25,000 diarrheal illnesses.
1976年8月3日，科罗拉多州正在进行的沙门氏菌监测首次发现了海德堡沙门氏菌感染疫情，最终共分离出339株菌株。大多数病例发生在7月23日至8月12日之间，分布在两个相距甚远的城市：丹佛和普韦布洛。流行病学调查先后认定了以下因素：1）近期在墨西哥风味餐厅就餐（p<0.001）；2）在这些餐厅食用含奶酪的食物（p = 0.029）；3）食用来自单一制造商一批次的切达干酪（p<0.01）。迅速展开的调查使得2087千克（41%）受污染奶酪被禁售。从七批涉案奶酪中分离出了海德堡沙门氏菌。监测和流行病学调查可能预防了25000例腹泻疾病的发生。
