Trompeter R S, Smith R L, Hoare R D, Neville B G, Chantler C
Arch Dis Child. 1982 Dec;57(12):913-7. doi: 10.1136/adc.57.12.913.
During a 10-year period 45 children were identified as having had neurological complications associated with severe arterial hypertension. Convulsions were the most common complication, occurring in 42 (82%) children. Two (4%) children each presented with a facial palsy and 2 (4%) with alterations in the level of consciousness. Nineteen (42%) presented with epileptic seizures as the first sign of arterial hypertension. The prognosis for children having had a single episode of hypertensive encephalopathy was good. Long-term follow-up showed no permanent neurological deficit on physical examination, and no focal abnormality on brain scan by computerised tomography. Psychometric analysis similarly failed to show any significant difference in cognitive assessment between children having had an episode of hypertensive encephalopathy and a control group with chronic renal disease, although reading skills were generally behind for chronological age and the average IQ was about 90 in both groups.
在10年期间,45名儿童被确定患有与严重动脉高血压相关的神经系统并发症。惊厥是最常见的并发症,42名(82%)儿童出现惊厥。两名(4%)儿童出现面瘫,两名(4%)儿童出现意识水平改变。19名(42%)儿童以癫痫发作作为动脉高血压的首发症状。患有单次高血压脑病的儿童预后良好。长期随访显示,体格检查未发现永久性神经功能缺损,计算机断层扫描脑部扫描未发现局灶性异常。心理测量分析同样未能显示患有高血压脑病的儿童与慢性肾病对照组在认知评估上有任何显著差异,尽管阅读技能通常落后于实际年龄,且两组的平均智商均约为90。