Burman S L, Ferrara L, Medhurst C L, Watson A D
Aust Vet J. 1982 Oct;59(4):118-20. doi: 10.1111/j.1751-0813.1982.tb02744.x.
Pyruvate kinase deficiency anaemia was suspected in an 18-month-old male Basenji dog after other known causes of canine haemolytic anaemia had been excluded. Anaemia of moderate severity (packed cell volumes 0.20 to 0.26 1/1) and reticulocytosis (uncorrected reticulocyte counts 8 to 43%) persisted during 5 months' observation, and biopsies showed development of bone marrow fibrosis and sclerosis. The diagnosis of pyruvate kinase deficiency anaemia was presumptive because erythrocyte pyruvate kinase concentrations in the affected dog were inconclusive and related animals were not available for enzyme assay. However, the gene for pyruvate kinase deficiency is known to occur among Basenji dogs in Australia.
在排除了其他已知的犬溶血性贫血病因后，怀疑一只18个月大的雄性巴仙吉犬患有丙酮酸激酶缺乏性贫血。在5个月的观察期内，中度贫血（红细胞压积0.20至0.26 1/1）和网织红细胞增多（未校正的网织红细胞计数8%至43%）持续存在，活检显示骨髓纤维化和硬化。丙酮酸激酶缺乏性贫血的诊断是推测性的，因为患病犬的红细胞丙酮酸激酶浓度不确定，且没有相关动物可用于酶测定。然而，已知丙酮酸激酶缺乏基因在澳大利亚的巴仙吉犬中存在。
