Lenney W, Milner A D
Arch Dis Child. 1978 Sep;53(9):704-6. doi: 10.1136/adc.53.9.704.
Total respiratory resistance (RT) was measured before and after nebulised alpha-adrenergic stimulant therapy in 8 children aged 4 to 18 months who had the clinical symptoms of acute viral croup. In 7 children there was a mean fall in RT of 30% after treatment, associated with an improvement in their clinical condition. This improvement was shortlived, the resistance returning to pretreatment levels within 30 minutes. The remaining child showed no improvement after phenylephrine but was subsequently found to have acute epiglottitis. Nebulised water did not produce any change, indicating that the response was not due to moisture alone.
对8名年龄在4至18个月、有急性病毒性喉炎临床症状的儿童,在雾化吸入α-肾上腺素能兴奋剂治疗前后测量了总呼吸阻力(RT)。7名儿童治疗后RT平均下降30%,同时临床状况有所改善。但这种改善是短暂的,阻力在30分钟内就恢复到治疗前水平。其余1名儿童使用去氧肾上腺素后没有改善,随后被发现患有急性会厌炎。雾化吸入水没有产生任何变化,这表明这种反应并非仅由水分引起。