18个月以下儿童毛细支气管炎和喘息性支气管炎中的α和β肾上腺素能兴奋剂
Alpha and beta adrenergic stimulants in bronchiolitis and wheezy bronchitis in children under 18 months of age.
作者信息
Lenney W, Milner A D
出版信息
Arch Dis Child. 1978 Sep;53(9):707-9. doi: 10.1136/adc.53.9.707.
Abstract
Total respiratory resistance was measured before and after nebulised phenylephrine in 5 babies (age range 7 to 17 months) with wheezy bronchitis, and in 2 babies (aged 2 and 6 months) with bronchiolitis. None showed a change in resistance after treatment. Total respiratory resistance was measured before and after nebulised adrenaline in another 14 babies (age range 4 to 13 months) with bronchiolitis. No fall in resistance was noted in any baby after treatment whether or not it was given by a conventional or an ultrasonic nebuliser. We conclude that alpha- and beta-adrenergic stimulants are ineffective in bronchiolitis and wheezy bronchitis in children under 18 months of age.
摘要
对5名患有喘息性支气管炎的婴儿（年龄范围7至17个月）和2名患有细支气管炎的婴儿（年龄分别为2个月和6个月），在雾化去氧肾上腺素前后测量了总呼吸阻力。治疗后均未显示阻力有变化。对另外14名患有细支气管炎的婴儿（年龄范围4至13个月），在雾化肾上腺素前后测量了总呼吸阻力。无论采用传统雾化器还是超声雾化器给药，治疗后均未发现任何婴儿的阻力下降。我们得出结论，α和β肾上腺素能兴奋剂对18个月以下儿童的细支气管炎和喘息性支气管炎无效。
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本文引用的文献
1
Oscillation mechanics of lungs and chest in man.人体肺部和胸部的振荡力学
J Appl Physiol. 1956 May;8(6):587-94. doi: 10.1152/jappl.1956.8.6.587.
2
Sympathomimetic drugs in acute viral bronchiolitis. Their effect on pulmonary resistance.急性病毒性细支气管炎中的拟交感神经药物。它们对肺阻力的影响。
Pediatrics. 1969 Oct;44(4):493-7.
3
Forced oscillation technique for determination of resistance to breathing in children.用于测定儿童呼吸阻力的强迫振荡技术
Arch Dis Child. 1973 Apr;48(4):259-66. doi: 10.1136/adc.48.4.259.
4
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5
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6
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Arch Dis Child. 1978 Jul;53(7):532-5. doi: 10.1136/adc.53.7.532.
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8
Influence of the pattern of structural growth of lung on susceptibility to specific infectious diseases in infants and children.
Pediatr Res. 1977 Mar;11(3 Pt 2):210-5.
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