18个月以下儿童毛细支气管炎和喘息性支气管炎中的α和β肾上腺素能兴奋剂
Alpha and beta adrenergic stimulants in bronchiolitis and wheezy bronchitis in children under 18 months of age.
作者信息
Lenney W, Milner A D
出版信息
Arch Dis Child. 1978 Sep;53(9):707-9. doi: 10.1136/adc.53.9.707.
Abstract
Total respiratory resistance was measured before and after nebulised phenylephrine in 5 babies (age range 7 to 17 months) with wheezy bronchitis, and in 2 babies (aged 2 and 6 months) with bronchiolitis. None showed a change in resistance after treatment. Total respiratory resistance was measured before and after nebulised adrenaline in another 14 babies (age range 4 to 13 months) with bronchiolitis. No fall in resistance was noted in any baby after treatment whether or not it was given by a conventional or an ultrasonic nebuliser. We conclude that alpha- and beta-adrenergic stimulants are ineffective in bronchiolitis and wheezy bronchitis in children under 18 months of age.
摘要
对5名患有喘息性支气管炎的婴儿（年龄范围7至17个月）和2名患有细支气管炎的婴儿（年龄分别为2个月和6个月），在雾化去氧肾上腺素前后测量了总呼吸阻力。治疗后均未显示阻力有变化。对另外14名患有细支气管炎的婴儿（年龄范围4至13个月），在雾化肾上腺素前后测量了总呼吸阻力。无论采用传统雾化器还是超声雾化器给药，治疗后均未发现任何婴儿的阻力下降。我们得出结论，α和β肾上腺素能兴奋剂对18个月以下儿童的细支气管炎和喘息性支气管炎无效。
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