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支气管扩张剂药物在什么年龄起作用?

At what age do bronchodilator drugs work?

作者信息

Lenney W, Milner A D

出版信息

Arch Dis Child. 1978 Jul;53(7):532-5. doi: 10.1136/adc.53.7.532.

Abstract

Using a modification of the forced oscillation technique we have measured respiratory resistance before and after nebulised salbutamol therapy in 32 wheezing children aged 7 months to 3 years 7 monts. 12 of the children were also studied in a total body plethysmograph. No child under 18 months of aged showed a greater than 5% fall in resistance or any fall in thoracic gas volume. In contrast, 18 of 20 children over 20 months of age showed a fall in resistance greater than 20%.

摘要

我们采用改良的强迫振荡技术,测量了32名年龄在7个月至3岁7个月的喘息儿童在雾化沙丁胺醇治疗前后的呼吸阻力。其中12名儿童还使用全身体积描记器进行了研究。18个月以下的儿童中,没有一名儿童的阻力下降超过5%,或胸腔气体容积下降。相比之下,20名20个月以上的儿童中有18名的阻力下降超过20%。

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At what age do bronchodilator drugs work?支气管扩张剂药物在什么年龄起作用?
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本文引用的文献

1
Oscillation mechanics of lungs and chest in man.人体肺部和胸部的振荡力学
J Appl Physiol. 1956 May;8(6):587-94. doi: 10.1152/jappl.1956.8.6.587.
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Lung volumes in exacerbations of asthma.哮喘加重期的肺容积
Am J Med. 1966 Aug;41(2):259-73. doi: 10.1016/0002-9343(66)90021-0.

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