Griss P, Werner E, Heimke G, Raute-Krenisen U
Arch Orthop Trauma Surg (1978). 1978 Aug 30;92(2-3):199-210. doi: 10.1007/BF00397960.
This report is based on 4 comparative experimental series is sheep using a cementfree total hip replacement model. Basically a smooth stem design was compared to a step stem design for biomechanical interlocking anchorage. Both designs were implanted as pure high density Al2O3-ceramic components and as Al2O3-ceramic parts coated with Bioglass or Bioglass-ceramic (post op. follow up 13 months, 17 animals). None of the 4 stem modifications showed a tendency for permanent stabilisation or bonding in bone. Besides insufficient bonding of the glass coatings to the substrate and apparent biodegradability of the bioglass coatings in the body, insufficient biomechanical knowledge of endosteal direct anchorage of prosthetic devices is the main reason for failure in these experiments. An exclusive biochemical way of anchoring prosthetic parts in the marrow cavity is rejected. The results presented are discussed in the light of the recent literature.
本报告基于在绵羊身上使用无水泥全髋关节置换模型进行的4个对比实验系列。基本上,将光滑柄设计与阶梯柄设计进行了生物力学互锁锚固比较。两种设计均作为纯高密度Al2O3陶瓷部件以及涂有生物玻璃或生物玻璃陶瓷的Al2O3陶瓷部件植入(术后随访13个月,17只动物)。4种植入柄的改进设计均未显示出在骨中永久稳定或结合的趋势。除了玻璃涂层与基底结合不足以及生物玻璃涂层在体内明显的生物降解性外,对假体装置骨内膜直接锚固的生物力学知识不足是这些实验失败的主要原因。排除了在骨髓腔中仅通过生化方式固定假体部件的方法。根据最近的文献对给出的结果进行了讨论。