Wilczek J
Acta Physiol Pol. 1982 Jul-Aug;33(4):265-72.
Rats were given adrenaline in continuous intravenous infusion at a rate of 10 micrograms/kg/min for 5 and 8 minutes. The phosphorolytic and hydrolytic activity in the myocardium and skeletal muscle was determined by the method of simultaneous measurements at one-minute intervals. In the adrenalectomized rats the effect of the adrenaline-hydrocortisone interaction on these activities was investigated. The obtained results confirmed the validity of the hypothesis about a correlation between the changes in the amylolytic activity and the phosphorolytic activity, and demonstrated that this correlation was not changed by glycocorticosteroids. A significant temporal correlation was found between the dynamics of the mutually opposite changes in both these glycogenolytic activities. The hypothesis of a competition between amylolysis and glycogen phosporolysis is discussed assuming that this would help in the maintenance of a relative equilibrium between glycogen biosynthesis and breakdown.
以10微克/千克/分钟的速率持续静脉输注肾上腺素，对大鼠进行5分钟和8分钟的处理。通过每隔一分钟同步测量的方法，测定心肌和骨骼肌中的磷酸解和水解活性。在肾上腺切除的大鼠中，研究了肾上腺素 - 氢化可的松相互作用对这些活性的影响。所得结果证实了关于淀粉分解活性变化与磷酸解活性之间相关性的假设的有效性，并表明这种相关性不受糖皮质激素的影响。在这两种糖原分解活性的相互相反变化的动态之间发现了显著的时间相关性。讨论了淀粉分解和糖原磷酸解之间竞争的假设，认为这有助于维持糖原生物合成与分解之间的相对平衡。
