Eckstein E C
Biorheology. 1982;19(6):717-24. doi: 10.3233/bir-1982-19605.
Interactions among red cells and platelets in flowing blood result in significant dispersive motions of the platelets, which are commonly modelled by an effective diffusion coefficient. This paper examines an additional platelet flux, termed rheophoresis, to model platelet motions due to the gradient of hematocrit. Rheophoretic effects occur near walls because geometric exclusion and fluid mechanical repulsion of red cells create a hematocrit gradient there. Models using rheophoretic flux show that platelet concentration near walls is elevated; such models provide a consistent interpretation of available experimental data. Estimates show the coefficients for traditional effective diffusivity and the rheophoretic diffusivity have similar magnitudes. The effects of rheophoresis on axial development of platelet concentration profiles and on surface deposition are discussed.
流动血液中红细胞与血小板之间的相互作用会导致血小板显著的离散运动，通常用有效扩散系数对其进行建模。本文研究了一种额外的血小板通量，称为流变电泳，以模拟由于血细胞比容梯度引起的血小板运动。流变电泳效应发生在壁面附近，因为红细胞的几何排斥和流体力学排斥在那里产生了血细胞比容梯度。使用流变电泳通量的模型表明，壁面附近的血小板浓度会升高；此类模型为现有实验数据提供了一致的解释。估计结果表明，传统有效扩散系数和流变电泳扩散系数的大小相似。文中还讨论了流变电泳对血小板浓度分布轴向发展以及对表面沉积的影响。
