Goodlin R, Kurpershoek C, Haesslein H
Clin Exp Hypertens B. 1982;1(1):49-56. doi: 10.3109/10641958209037180.
Colloid osmotic pressure (COP) was measured in maternal serum of normal and hypertensive gravidae, and in their amniotic fluid. Both normal and hypertensive gravidae in the third trimester at bed rest and those treated for hypertension have low COP. Likewise, postpartum women may have low serum COP values apparently unrelated to any disease process. Amniotic fluid COP is low in both normal and hypertensive gravidae. COP Measurements therefore, seemingly offers little information regarding the health of pregnant women. Serum COP may increase in some hypertensive gravidae receiving saline infusion, probably reflecting abnormal renal function and hypovolemia. High serum triglyceride values coexisting with low COP may represent hepatic efforts to produce other colloid osmotic-active substances in the semi-chronic situation, although our findings in the acute situation did not support this hypothesis.
在正常孕妇和高血压孕妇的母血及其羊水样本中测量了胶体渗透压（COP）。妊娠晚期卧床休息的正常孕妇和高血压孕妇以及接受高血压治疗的孕妇的COP均较低。同样，产后女性的血清COP值可能较低，这显然与任何疾病过程无关。正常孕妇和高血压孕妇的羊水COP均较低。因此，COP测量似乎对孕妇健康状况提供的信息很少。一些接受盐水输注的高血压孕妇的血清COP可能会升高，这可能反映了肾功能异常和血容量不足。尽管我们在急性情况下的研究结果不支持这一假设，但在半慢性情况下，高血清甘油三酯值与低COP并存可能代表肝脏努力产生其他具有胶体渗透活性的物质。
