休克与复苏。III. 用HALFD治疗低血容量时准确的折射法测定胶体渗透压

Shock and resuscitation. III. Accurate refractometric COP determinations in hypovolemia treated with HALFD.

作者信息

Jelenko C, Solenberger R I, Wheeler M L, Callaway B D

出版信息

JACEP. 1979 Jul;8(7):253-6. doi: 10.1016/s0361-1124(79)80218-x.

Abstract

In 38 critically burned patients with symptomatic hypovolemia being treated by intravenous fluids, the accuracy of colloid oncotic pressure (COP) calculated from the refractometrically-determined serum total protein (TPRI) was compared with COP values determined by a commercially-available clinical oncometer. Sera were obtained randomly from seven patients receiving Ringer's lactate solution, five receiving a hypertonic solution (240 mOsm Na+) and 26 receiving a hypertonic solution containing albumin (12.5 gm/liter, HALFD method). There was poor correlation between COP measure and that calculated from RI in patients receiving colloid-free fluid, but high correlation (r = 0.925) in patients receiving HALFD. There was high correlation (r = 0.951) between measured COP and values calculated from TPRI in patients receiving hypertonic fluid, colloid containing hypertonic fluid, or no fluid:COP = 4.08 (TPRI)--4.61.

摘要

在38例接受静脉补液治疗的有症状性低血容量的重症烧伤患者中，将通过折射法测定的血清总蛋白（TPRI）计算得出的胶体渗透压（COP）的准确性与通过市售临床渗透压计测定的COP值进行了比较。随机从7例接受乳酸林格氏液的患者、5例接受高渗溶液（240 mOsm Na +）的患者和26例接受含白蛋白高渗溶液（12.5 g/升，HALFD法）的患者中获取血清。在接受无胶体液体的患者中，COP测量值与根据RI计算得出的值之间相关性较差，但在接受HALFD的患者中相关性较高（r = 0.925）。在接受高渗液体、含胶体高渗液体或无液体的患者中，测量的COP与根据TPRI计算的值之间相关性较高（r = 0.951）：COP = 4.08（TPRI） - 4.61。