Nyeem R, Wilkinson E J, Grover L J
Int J Gynecol Pathol. 1982;1(3):246-57. doi: 10.1097/00004347-198203000-00002.
Cervical specimens from 531 consecutive cases were reviewed to determine the frequency of cervical condylomata acuminata (CLA) and their association with cervical intraepithelial neoplasia (CIN). CLA and CIN were subclassified into three groups based on the criteria previously established in the literature. Our data indicate that CLA was present in 103 (19%) cases and that 44 (43%) of these had CIN as well. The total number of cases of CIN in this series was 146 (27%) with 44 of these (30%) having associated CLA. Of the eight CIN cases in women under 20 years of age, seven (99.6%) had associated CLA. The mean age of patients with CIN alone was 31 years; patients with CIN and CLA were younger, with a mean age of 24 years. These findings indicate that cervical CLA is a common lesion affecting young women and that there is a significant association of CLA with CIN. Women with CLA appear to be at significant risk for development of CIN.
对531例连续病例的宫颈标本进行回顾，以确定宫颈尖锐湿疣（CLA）的发生率及其与宫颈上皮内瘤变（CIN）的关联。根据先前文献中确立的标准，将CLA和CIN分为三组。我们的数据表明，103例（19%）病例存在CLA，其中44例（43%）同时患有CIN。本系列中CIN病例总数为146例（27%），其中44例（30%）伴有CLA。在20岁以下女性的8例CIN病例中，7例（99.6%）伴有CLA。单纯CIN患者的平均年龄为31岁；CIN合并CLA患者更年轻，平均年龄为24岁。这些发现表明，宫颈CLA是一种影响年轻女性的常见病变，且CLA与CIN之间存在显著关联。患有CLA的女性似乎有发生CIN的显著风险。
