van Dongen P W, van't Hof M A
Med J Zambia. 1982 May-Jul;16(3):58-62.
IN a sample of 424 Zambian pregnant women a series of tests were made: sickle cell test, haemoglobin and packed cell volume estimations and screening of a thick blood smear for malaria and a thin blood smear for the presence of signs of anaemia. More anaemia was found in the primigravidae than in the multigravidae. The Hb-level was found to be lower with primigravidity and independently of this gravidity effect, also with malaria. Taking into account the higher malaria frequency in primigravidae, this group must be considered as a high risk group for the development of anaemia. The presence of the sickle cell trait was shown to have no effect on anaemia and malaria. In addition to the tests during pregnancy, the placentae and umbilical cords of 155 women were screened for malaria, as were the mothers just before delivery. More malaria parasites were detected in the placenta of the primiparous as compared with the multiparous women. Peripheral parasitaemia was strikingly less prevalent than infestation of the placenta.
在424名赞比亚孕妇样本中进行了一系列检测：镰状细胞检测、血红蛋白和红细胞压积测定，以及厚血涂片疟疾筛查和薄血涂片贫血体征筛查。初产妇中发现的贫血情况比经产妇更多。发现初孕时血红蛋白水平较低，且独立于这种妊娠影响之外，疟疾也会导致血红蛋白水平降低。考虑到初产妇中疟疾发病率较高，该群体必须被视为贫血发展的高危群体。镰状细胞性状的存在对贫血和疟疾没有影响。除了孕期检测外，还对155名妇女的胎盘和脐带进行了疟疾筛查，产妇在分娩前也接受了筛查。与经产妇相比，初产妇胎盘中检测到的疟原虫更多。外周血寄生虫血症的发生率明显低于胎盘感染率。
