Zawadowski T, Kossakowski J
Pol J Pharmacol Pharm. 1982 Nov-Dec;34(5-6):433-40.
Aminoesters of the following acids were obtained: 4,6-diacetyl-5-hydroxy- and -5-methoxy-2-methylbenzofuran-3-carboxylic, 5,7-diacetyl-6-hydroxy- and -6-methoxy 3 methylbenzofuran-2-carboxylic, 6-hydroxy-7-p-methoxy-3-methylcinnamoyl-coumarilic and 4,7-dimethoxy-6-hydroxybenzofuran-5-carboxylic. The hydrochlorides of these aminoesters displayed hypotensive and antiarrhythmic activity in doses of 5-10 mg/kg.
4,6 - 二乙酰基 - 5 - 羟基 - 和 - 5 - 甲氧基 - 2 - 甲基苯并呋喃 - 3 - 羧酸、5,7 - 二乙酰基 - 6 - 羟基 - 和 - 6 - 甲氧基 - 3 - 甲基苯并呋喃 - 2 - 羧酸、6 - 羟基 - 7 - 对甲氧基 - 3 - 甲基肉桂酰基 - 香豆酸以及4,7 - 二甲氧基 - 6 - 羟基苯并呋喃 - 5 - 羧酸。这些氨基酯的盐酸盐在剂量为5 - 10毫克/千克时表现出降压和抗心律失常活性。
