Strian F, Heger R, Klicpera C
Acta Psychiatr Scand. 1982 Jan;65(1):66-73. doi: 10.1111/j.1600-0447.1982.tb00821.x.
This research focused on the depressive mood of 134 inpatients with a diagnosis of schizophrenia. All of the patients filled in a self-rating mood scale (Befindlichkeits-Skala by von Zerssen) every other day. The frequency of depressive mood and the intensity and dynamics of each period of depression were analysed with the aid of defined algorithms. Marked depression was found in more than half of the patients. Depression was seen predominantly at the beginning of hospitalization, and subsequent occurrences were not concentrated in any specific time periods. The results suggested that depression in schizophrenia is predominantly an experience or consequence of the underlying illness and that pharmacological factors are not of as great importance as has been thus far assumed in the literature.
这项研究聚焦于134名被诊断为精神分裂症的住院患者的抑郁情绪。所有患者每隔一天填写一份自评情绪量表（冯·策尔森编制的情绪量表）。借助特定算法分析抑郁情绪的发生频率以及每个抑郁阶段的强度和变化情况。超过半数的患者存在明显抑郁。抑郁主要出现在住院初期，后续发作并未集中在任何特定时间段。结果表明，精神分裂症中的抑郁主要是潜在疾病的一种体验或后果，而且药理学因素并不像迄今为止文献中所假设的那么重要。
