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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Reddy P V, Sastry P S

Br J Nutr. 1978 Nov;40(3):403-11. doi: 10.1079/bjn19780141.

Phospholipid content of brains of 3- or 8-week-old undernourished rats was 7--9% less than that for the corresponding control animals and this deficit could not be made up by rehabilitation. Phosphatidyl ethanolamine and plasmalogen were the components most affected in brains of undernourished rats. 2. Incorporation of 32P into phospholipids by brain homogenates was 28% higher in 3-week-old undernourished rats. It is suggested that enhanced phospholipid metabolism in undernourished animals may be related to behavioural alterations noted previously (Sobotka, Cook & Brodie, 1974). 3. Ganglioside concentrations in 3- and 8-week-old undernourished animals were 14% and 11.5% less respectively than those of the control animals and this difference could be made up by rehabilitation. [14C]Glucosamine incorporation in vivo into brain gangliosides was not affected by undernutrition.

3周龄或8周龄营养不良大鼠大脑的磷脂含量比相应的对照动物低7%-9%，且这种缺乏无法通过恢复营养来弥补。磷脂酰乙醇胺和缩醛磷脂是营养不良大鼠大脑中受影响最大的成分。2. 3周龄营养不良大鼠大脑匀浆将³²P掺入磷脂的量高出28%。有人提出，营养不良动物中增强的磷脂代谢可能与先前观察到的行为改变有关（索博特卡、库克和布罗迪，1974年）。3. 3周龄和8周龄营养不良动物的神经节苷脂浓度分别比对照动物低14%和11.5%，这种差异可通过恢复营养来弥补。体内[¹⁴C]葡糖胺掺入大脑神经节苷脂不受营养不足的影响。

Reddy P V, Sastry P S

Br J Nutr. 1978 Nov;40(3):403-11. doi: 10.1079/bjn19780141.

Phospholipid content of brains of 3- or 8-week-old undernourished rats was 7--9% less than that for the corresponding control animals and this deficit could not be made up by rehabilitation. Phosphatidyl ethanolamine and plasmalogen were the components most affected in brains of undernourished rats. 2. Incorporation of 32P into phospholipids by brain homogenates was 28% higher in 3-week-old undernourished rats. It is suggested that enhanced phospholipid metabolism in undernourished animals may be related to behavioural alterations noted previously (Sobotka, Cook & Brodie, 1974). 3. Ganglioside concentrations in 3- and 8-week-old undernourished animals were 14% and 11.5% less respectively than those of the control animals and this difference could be made up by rehabilitation. [14C]Glucosamine incorporation in vivo into brain gangliosides was not affected by undernutrition.

3周龄或8周龄营养不良大鼠大脑的磷脂含量比相应的对照动物低7%-9%，且这种缺乏无法通过恢复营养来弥补。磷脂酰乙醇胺和缩醛磷脂是营养不良大鼠大脑中受影响最大的成分。2. 3周龄营养不良大鼠大脑匀浆将³²P掺入磷脂的量高出28%。有人提出，营养不良动物中增强的磷脂代谢可能与先前观察到的行为改变有关（索博特卡、库克和布罗迪，1974年）。3. 3周龄和8周龄营养不良动物的神经节苷脂浓度分别比对照动物低14%和11.5%，这种差异可通过恢复营养来弥补。体内[¹⁴C]葡糖胺掺入大脑神经节苷脂不受营养不足的影响。