双胞胎研究与血小板单胺氧化酶活性的底物差异
Twin studies and substrate differences in platelet monoamine oxidase activity.
作者信息
Hussein L, Sindarto E, Goedde H W
出版信息
Hum Hered. 1980;30(2):65-70. doi: 10.1159/000153104.
PMID:7188930
Abstract
Monoamine oxidase activity was measured in blood platelets of 7 pairs of identical (MZ) twins and a similar number of age- and sex-matched control pairs. Mean intrapair difference in platelet MAO activity was significantly smaller (0.01 less than p less than 0.025) in MZ compared to controls. Kinetic studies of the enzyme revealed mean Km value of 1.0 x 10(-5) mol/l for tryptamine. Platelet MAO activity is higher in women than in men.
摘要
在7对同卵（MZ）双胞胎以及数量相近的年龄和性别匹配的对照对的血小板中测量了单胺氧化酶活性。与对照组相比，MZ双胞胎血小板单胺氧化酶活性的平均配对内差异显著更小（0.01＜p＜0.025）。该酶的动力学研究表明，色胺的平均米氏常数为1.0×10⁻⁵mol/l。女性的血小板单胺氧化酶活性高于男性。
Zotero 插件