患 Wiedemann-Beckwith 综合征不一致的同卵双胞胎及其对遗传咨询的意义。
Monozygotic twins discordant for Wiedemann-Beckwith syndrome and the implications for genetic counselling.
作者信息
Berry A C, Belton E M, Chantler C
出版信息
J Med Genet. 1980 Apr;17(2):136-8. doi: 10.1136/jmg.17.2.136.
Abstract
A pair of monozygous twins discordant for Wiedemann-Beckwith syndrome is described and published reports reviewed to establish the mode of inheritance. Single gene control seems unlikely and it is proposed that the condition arises from the interaction of "at risk" genes in the fetus and metabolic factors in the mother, which suggests multifactorial control.
摘要
本文描述了一对患维德曼-贝克威思综合征的单卵双胞胎，并回顾了已发表的报告以确定其遗传模式。单基因控制似乎不太可能，有人提出这种情况是由胎儿中“有风险”的基因与母亲体内的代谢因素相互作用引起的，这表明是多因素控制。
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Monozygotic twins discordant for Wiedemann-Beckwith syndrome and the implications for genetic counselling.患 Wiedemann-Beckwith 综合征不一致的同卵双胞胎及其对遗传咨询的意义。
J Med Genet. 1980 Apr;17(2):136-8. doi: 10.1136/jmg.17.2.136.
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Letter: Pseudo-Beckwith-Wiedemann syndrome: interaction with maternal diabetes.信件：假性贝克威思-维德曼综合征：与母亲糖尿病的相互作用。
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The Wiedemann-Beckwith syndrome: genetic considerations and a diagnostic sign.维德曼-贝克威思综合征：遗传学考量及一种诊断体征。
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