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[吉地芬对情绪应激反应的行为和血流动力学指标的影响]

[Effect of gidifen on behavior and hemodynamic signs of an emotionally stressful reaction].

作者信息

Val'dman A V, Kozlovskaia M M, Zaikonnikova I V, Bravkov M F, Rzhevskaia G F

出版信息

Biull Eksp Biol Med. 1980 Mar;89(3):310-2.

PMID:7190040
Abstract

Gidifen (diphenylphosphinylacetic acid hydrazide) is an original Soviet tranquilizer. In doses of 120--150 mg/kg it restores central baroreflex regulation of the arterial pressure supressed during acute emotional-stress reaction in cats (confrontation with a dog). The drug has an antihypertensive action and reduces tachycardia caused by the emotional stress. It has a selective antiphobic and antiaggressive action and does not produce ataxia. Quantitative evaluation of behavior was performed during group interaction of animals according to the five-point system.

摘要

吉地芬(二苯基磷酰基乙酸酰肼)是一种原苏联的镇静剂。在剂量为120 - 150毫克/千克时,它能恢复猫在急性情绪应激反应(与狗对峙)期间被抑制的动脉血压的中枢压力反射调节。该药物具有降压作用,并能减轻由情绪应激引起的心动过速。它具有选择性抗恐惧和抗攻击作用,且不会引起共济失调。根据五分制在动物群体互动期间对行为进行了定量评估。

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