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肺血管中与年龄相关的内膜纤维化的超微结构

The ultrastructure of age-associated intimal fibrosis in pulmonary blood vessels.

作者信息

Smith P, Heath D

出版信息

J Pathol. 1980 Apr;130(4):247-53. doi: 10.1002/path.1711300406.

DOI:10.1002/path.1711300406
PMID:7190189
Abstract

The pulmonary blood vessels were examined from five human lungs surgically resected for bronchial carcinoma. Age-associated intimal fibrosis in these vessels was acellular in veins but more cellular in muscular pulmonary arteries. In both classes of vessel the cell involved in the production of this fibrosis was the myofibroblast, a cell which shares the properties of fibroblast and smooth muscle. The endothelial cells of pulmonary arteries contained numerous, uniform filaments with a random orientation but such filaments were rare in veins.

摘要

对五例因支气管癌而手术切除的人肺中的肺血管进行了检查。这些血管中与年龄相关的内膜纤维化在静脉中无细胞,但在肌性肺动脉中细胞较多。在这两类血管中,参与这种纤维化形成的细胞都是肌成纤维细胞,这是一种兼具成纤维细胞和平滑肌特性的细胞。肺动脉的内皮细胞含有大量均匀的、随机排列的细丝,但在静脉中这种细丝很少见。

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