Warnock M L, Kunzmann A
Arch Pathol Lab Med. 1977 Apr;101(4):175-9.
The mean wall thickness, in relation to the external diameter, of 100 muscular arteries distended by barium gelatin at 100cm H2O pressure was calculated in "normal" lungs from patients who ranged in age from 3 to 79 years. For normal vessels less than 2 mm in diameter the mean was 2.4% of the external diameter. The mean for vessels in the five persons under 40 years was 1.8% but it was 2.8% for the five older individuals. Although this difference may reflect some increased muscularity with age, some of the increment may be related to a reduced distensibility of vessels caused by the accumulation of interstitial fluid, as manifested by increased weight in the older lungs. Intimal fibrosis was found to increase with age but occurred in less than 50% of the vessels measured.
在100cm水柱压力下用钡明胶扩张的100条肌性动脉的平均壁厚与外径之比，是从年龄在3至79岁的患者的“正常”肺中计算得出的。对于直径小于2mm的正常血管，平均值为外径的2.4%。40岁以下五人的血管平均值为1.8%，但五名年长者的血管平均值为2.8%。尽管这种差异可能反映了随着年龄增长肌肉量有所增加，但部分增加可能与间质液积聚导致血管扩张性降低有关，这在年长的肺中表现为重量增加。发现内膜纤维化随年龄增加，但在所测量的血管中发生率不到50%。
