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天然抗肿瘤药物的微生物转化。13. β-位受阻蒽环酮的转化

Microbial transformations of natural antitumor agents. 13. Conversions of 13-blocked anthracyclinones.

作者信息

Wu G S, Gard A, Rosazza J P

出版信息

J Antibiot (Tokyo). 1980 Jul;33(7):705-10. doi: 10.7164/antibiotics.33.705.

DOI:10.7164/antibiotics.33.705
PMID:7190964
Abstract

Microbial transformation experiments were performed using 13-ketone-blocked daunomycinone derivatives which were converted into the corresponding carminomycinone derivatives by microbial O-demethylation.

摘要

使用13-酮基封闭的柔红霉素酮衍生物进行微生物转化实验，这些衍生物通过微生物O-去甲基化转化为相应的洋红霉素酮衍生物。

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Microbial transformation of semisynthetic derivatives of daunomycinone modified in ring A.
Folia Microbiol (Praha). 1989;34(5):459-62. doi: 10.1007/BF02820754.