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[几种激素对实验性自由基脂质氧化反应强度的影响]

[Effect of several hormones on the intensity of experimental free-radical lipid oxidation reactions].

作者信息

Kulikov V Iu, Kaznacheev V P, Stiukhliaev V P, Kolesnikova L I, Molchanova L V

出版信息

Biull Eksp Biol Med. 1978 Nov;86(11):531-3.

PMID:719144
Abstract

The effect of adrenaline and hydrocortisone on the processes of free radical oxidation of lipids in rabbit erythrocytes was studied in experiment in vivo against the background of altered lipid metabolism. Adrenaline in a dose of 0.1 mg/kg and hydrocortisone in a dose of 5 mg/kg induced an increase in the amount of hydroperoxidase of fatty acids recorded by the changes of the UV spectrum. The data obtained served in confirmation of the fact that adrenaline and hydrocortisone possessed prooxidant properties, apparently mediated, this being connected with their fat mobilizing effects.

摘要

在脂质代谢改变的背景下,在体内实验中研究了肾上腺素和氢化可的松对兔红细胞脂质自由基氧化过程的影响。剂量为0.1mg/kg的肾上腺素和剂量为5mg/kg的氢化可的松可导致通过紫外光谱变化记录的脂肪酸氢过氧化物酶量增加。所获得的数据证实了肾上腺素和氢化可的松具有促氧化特性这一事实,显然是由它们的脂肪动员作用介导的,这与之相关。

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