Kvam G
Acta Radiol Diagn (Stockh). 1980;21(3):357-74. doi: 10.1177/028418518002100305.
Left ventricular cineangiographic data from 4 patients with idiopathic hypertrophic subaortic stenosis (IHSS) and 10 control patients have been analysed by means of geometric models. The myocardial fibre shortening of the free left ventricular wall in IHSS has been compared with the fibre shortening of the left ventricular wall in the control group. During the first half of systole, the fibre shortening occurs equally fast in the two groups, but during the second half it lags clearly behind in the IHSS group. The stroke volume is ejected much faster in the IHSS group and the ejection fraction is much higher. This is caused by several factors related to both functional and anatomic derangements of the left ventricle and the interventriclar septum: (1) A hypertrophic septum contracting isometrically with no persisting concavity away from the left ventricular cavity, acting as a suspender, and the posterior wall encroaching upon the septum in a slit-like manner. (2) Some increase in septal thickness narrowing the ventricular cavity. (3) A hypertrophic nonseptal ventricular wall. (4) A long ventricular cavity relative to the width. (5) A shallow left ventricular cavity. (6) A somewhat smaller EDV than normal.
已通过几何模型对4例特发性肥厚性主动脉瓣下狭窄（IHSS）患者和10例对照患者的左心室心血管造影数据进行了分析。将IHSS患者左心室游离壁的心肌纤维缩短情况与对照组左心室壁的纤维缩短情况进行了比较。在收缩期的前半段，两组的纤维缩短速度相同，但在收缩期的后半段，IHSS组明显滞后。IHSS组的每搏输出量射出速度更快，射血分数更高。这是由与左心室和室间隔的功能及解剖紊乱相关的几个因素导致的：（1）肥厚的室间隔等长收缩，没有持续远离左心室腔的凹陷，起到了悬吊作用，后壁以狭缝状方式向室间隔 encroaching upon。（2）室间隔厚度有所增加，使心室腔变窄。（3）肥厚的非室间隔心室壁。（4）相对于宽度而言较长的心室腔。（5）较浅的左心室腔。（6）舒张末期容积（EDV）比正常情况略小。 （注：encroaching upon这个词在原文中似乎不太完整，推测可能是“ encroaching upon the septum”，即“向室间隔 encroaching upon”，翻译时保留了原文的不完整性。）
