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新生儿肠道激素对进食的反应发育

Development of gut hormone responses to feeding in neonates.

作者信息

Lucas A, Bloom S R, Aynsley-Green A

出版信息

Arch Dis Child. 1980 Sep;55(9):678-82. doi: 10.1136/adc.55.9.678.

Abstract

The development of the effects of a human milk feed on plasma concentrations of motilin, neurotensin, gastric inhibitory polypeptide, enteroglucagon, gastrin, and secretin were studied in 158 healthy preterm neonates (mean gestation 33 1/2 weeks) at mean postnatal ages of 2 1/2, 6, 13, or 24 days. Pronounced progressive changes occurred in postprandial hormone responses; these were absent or small in the first days of life and were large by age 24 days. These changes may have important consequences in the adaptation to postnatal life.

摘要

在158名健康的早产新生儿(平均孕周33.5周)中,研究了母乳喂养对胃动素、神经降压素、胃抑制多肽、肠高血糖素、胃泌素和促胰液素血浆浓度的影响,这些新生儿的平均出生后年龄分别为2.5天、6天、13天或24天。餐后激素反应出现了明显的渐进性变化;这些变化在生命的最初几天不存在或很小,到24天时则很大。这些变化可能对适应出生后的生活有重要影响。

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引用本文的文献

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Arch Dis Child. 1991 Jan;66(1 Spec No):17-20. doi: 10.1136/adc.66.1_spec_no.17.

本文引用的文献

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Plasma secretin in neonates.新生儿血浆促胰液素
Acta Paediatr Scand. 1980 Mar;69(2):205-10. doi: 10.1111/j.1651-2227.1980.tb07061.x.
4
Breast vs bottle: endocrine responses are different with formula feeding.
Lancet. 1980 Jun 14;1(8181):1267-9. doi: 10.1016/s0140-6736(80)91731-6.
5
Glucose tolerance and plasma insulin in newborn infants of normal and diabetic mothers.
Pediatr Res. 1968 May;2(3):198-208. doi: 10.1203/00006450-196805000-00007.
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Neonatal secretion of gastrin and glucagon.新生儿胃泌素和胰高血糖素的分泌。
Arch Dis Child. 1974 Oct;49(10):796-801. doi: 10.1136/adc.49.10.796.

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