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[通过给予抗原和免疫刺激剂在小鼠中诱导可移植性白血病样综合征]

[Induction of transplantable leukemia-like syndromes in mice by administration of antigens and immunostimulants].

作者信息

Denner I

出版信息

Biull Eksp Biol Med. 1977 Sep;84(9):344-6.

PMID:71928
Abstract

Splenomegaly characterised by myeloid metaplasia was induced in BALB/c mice by the injection of antigens and immunostimulants. In difference from leukemoid reaction, this syndrome was transmissible both by the plasma and by the splenic cells. Small virus-like particles (30--50 nm) were revealed in the plasma, and RNA-containing viruses of type C--in the splenic cells.

摘要

通过注射抗原和免疫刺激剂,在BALB/c小鼠中诱导出以髓外化生为特征的脾肿大。与类白血病反应不同,该综合征可通过血浆和脾细胞传播。在血浆中发现了小的病毒样颗粒(30 - 50纳米),在脾细胞中发现了C型含RNA病毒。

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