Hladoń B, Bylka W, Ellnain-Wojtaszek M, Skrzypczak L, Szafarek P, Chodera A, Kowalewski Z
Arzneimittelforschung. 1980;30(11):1847-8.
Extracts from propolis have been investigated for cytostatic activity in vitro, by method of tissue culture on human KB and HeLa cell lines. Diethyl ether extract (DEEP) sowed the greatest activity and therefore it was further fractionated. Secondary DEEP fractions obtained by extraction with BuOH (ED50 = 2.6 micrograms/ml) and AcOEt (ED50 = 3.3 micrograms/ml) have been qualified to further in vivo studies.
通过在人KB和HeLa细胞系上进行组织培养的方法，对蜂胶提取物的体外细胞抑制活性进行了研究。乙醚提取物（DEEP）表现出最大的活性，因此对其进行了进一步分离。用BuOH（ED50 = 2.6微克/毫升）和AcOEt（ED50 = 3.3微克/毫升）萃取得到的DEEP二级馏分已具备进一步进行体内研究的条件。
