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大鼠发情周期中离散下丘脑核团内β-内啡肽含量的变化。

Changes in the beta-endorphin content of discrete hypothalamic nuclei during the estrous cycle of the rat.

作者信息

Barden N, Mérand Y, Rouleau D, Garon M, Dupont A

出版信息

Brain Res. 1981 Jan 12;204(2):441-5. doi: 10.1016/0006-8993(81)90605-3.

DOI:10.1016/0006-8993(81)90605-3
PMID:7193067
Abstract

Concentrations of beta-endorphin were measured in discrete brain nuclei of 4-day cycling rats on each day of the estrous cycle. On the afternoon of proestrus beta-endorphin levels were significantly higher in median eminence and suprachiasmatic nucleus, and lower in arcuate nucleus, when compared to levels found on other days of the cycle. These changes coincided with the peak of plasma prolactin, which was blocked by prior administration of naloxone.

摘要

在动情周期的每一天,测量4日龄周期性发情大鼠离散脑核中的β-内啡肽浓度。与动情周期其他日子的水平相比,在动情前期的下午,正中隆起和视交叉上核中的β-内啡肽水平显著升高,而弓状核中的β-内啡肽水平降低。这些变化与血浆催乳素的峰值一致,而该峰值可被预先给予的纳洛酮阻断。

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