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大鼠离散脑核中β-内啡肽含量的年龄依赖性变化。

Age-dependent changes in the beta-endorphin content of discrete rat brain nuclei.

作者信息

Barden N, Dupont A, Labrie F, Mérand Y, Rouleau D, Vaudry H, Boissier J R

出版信息

Brain Res. 1981 Mar 9;208(1):209-12. doi: 10.1016/0006-8993(81)90634-x.

Abstract

Concentrations of beta-endorphin were measured by radioimmunoassay in discrete brain nuclei of young (3 months) and old (24 months) rats. The beta-endorphin content of all major structures known to contain this peptide with the exception of the eminence, is reduced (50.3 +/- 2.8% of control) in old rats.

摘要

通过放射免疫分析法测定了年轻(3个月)和年老(24个月)大鼠离散脑核中β-内啡肽的浓度。除隆起外,已知含有这种肽的所有主要结构中的β-内啡肽含量在老年大鼠中均降低(为对照的50.3±2.8%)。

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