热量、锌、维生素A和吡哆醇缺乏时的血清胸腺因子活性
Serum thymic factor activity in deficiencies of calories, zinc, vitamin A and pyridoxine.
作者信息
Chandra R K, Heresi G, Au B
出版信息
Clin Exp Immunol. 1980 Nov;42(2):332-5.
Abstract
Cell-mediated immunity is invariably impaired in protein-energy malnutrition. The effect of selected nutrient deficiencies on serum thymic factor activity was assessed in deprived rats and pair-fed controls. Deficits of calories, zinc or pyridoxine resulted in significant lowering of serum thymic factor activity whereas vitamin A deficiency did not have any effect. It is suggested that variants nutrients modulate different steps of cell-mediated immunity and that reduced thymic hormone activity may be the underlying mechanism of imparied immunity in some but not all nutritional deficiencies.
摘要
在蛋白质-能量营养不良中，细胞介导的免疫总是受损。在营养缺乏的大鼠和配对喂养的对照组中评估了特定营养素缺乏对血清胸腺因子活性的影响。热量、锌或维生素B6缺乏导致血清胸腺因子活性显著降低，而维生素A缺乏则没有任何影响。有人提出，不同的营养素调节细胞介导免疫的不同步骤，胸腺激素活性降低可能是某些（但不是所有）营养缺乏中免疫受损的潜在机制。
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