Clarke J D, Coleman G J, Armstrong S
Int J Chronobiol. 1981;7(3):145-52.
The possibility that daily food and water presentation is a more potent synchronizer to the estrual rhythm of the female rat than the light-dark cycle was investigated by presenting food and water ad libitum only during the dark period or only during the light period of an LD 12:12. It was found that the daily feeding and drinking regimes did not synchronize the estrous cycle, but only disrupted the synchrony between the LD cycle and the estrous cycle. Because there was no significant difference between body weights of the groups, results cannot be interpreted in terms of under-nourishment effects on hormone synthesis, but rather in terms of the temporal characteristics of food and water intake.
通过在12小时光照-12小时黑暗（LD 12:12）的黑暗期或仅在光照期随意提供食物和水，研究了每日食物和水供应对雌性大鼠发情周期而言是否比明暗周期更有效的同步器。结果发现，每日进食和饮水模式并未使发情周期同步，而是仅破坏了光照-黑暗周期与发情周期之间的同步性。由于各实验组大鼠体重之间无显著差异，因此结果不能从营养不足对激素合成的影响方面来解释，而应从食物和水摄入的时间特征方面来解释。
