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Infect Immun. 1981 May;32(2):480-3. doi: 10.1128/iai.32.2.480-483.1981.
2
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本文引用的文献

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Stimulation of adenyl cyclase by Escherichia coli enterotoxin.大肠杆菌肠毒素对腺苷酸环化酶的刺激作用。
Nat New Biol. 1972 Apr 5;236(66):137-8. doi: 10.1038/newbio236137a0.
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Elevated concentration of adenosine 3':5'-cyclic monophosphate in intestinal mucosa after treatment with cholera toxin.霍乱毒素处理后肠黏膜中3':5'-环磷酸腺苷浓度升高。
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Stimulation of intestinal adenyl cyclase by cholera toxin.霍乱毒素对肠道腺苷酸环化酶的刺激作用。
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Effect of chlorpromazine on the secretory activity of Escherichia coli heat-stable enterotoxin.氯丙嗪对大肠杆菌热稳定肠毒素分泌活性的影响。
Infect Immun. 1979 Dec;26(3):1000-3. doi: 10.1128/iai.26.3.1000-1003.1979.
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Purification and partial characterization of heat-stable enterotoxin of enterotoxigenic Escherichia coli.产肠毒素大肠杆菌热稳定肠毒素的纯化及部分特性研究
Infect Immun. 1979 Sep;25(3):978-85. doi: 10.1128/iai.25.3.978-985.1979.
8
Chlorpromazine reverses diarrhea in piglets caused by enterotoxigenic Escherichia coli.氯丙嗪可逆转由产肠毒素大肠杆菌引起的仔猪腹泻。
Infect Immun. 1979 Jun;24(3):900-5. doi: 10.1128/iai.24.3.900-905.1979.
9
Reversal of cyclic AMP-mediated intestinal secretion in mice by chlorpromazine.氯丙嗪对小鼠中环磷酸腺苷介导的肠道分泌的逆转作用。
Gastroenterology. 1978 Dec;75(6):1103-8.
10
Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli.
Nature. 1978 Feb 23;271(5647):755-6. doi: 10.1038/271755a0.

氯丙嗪未能抑制大肠杆菌热稳定肠毒素引起的乳鼠体液蓄积。

Failure of chlorpromazine to inhibit fluid accumulation caused by Escherichia coli heat-stable enterotoxin in suckling mice.

作者信息

Takeda T, Honda T, Takeda Y, Miwatani T

出版信息

Infect Immun. 1981 May;32(2):480-3. doi: 10.1128/iai.32.2.480-483.1981.

DOI:10.1128/iai.32.2.480-483.1981
PMID:7195875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC351470/
Abstract

We studied the effect of chlorpromazine on fluid accumulation caused by purified heat-stable enterotoxin (ST) from enterotoxigenic Escherichia coli in suckling mice. We found that chlorpromazine inactivated ST itself in vitro, but did not inhibit the activity of ST in the intestines.

摘要

我们研究了氯丙嗪对产肠毒素大肠杆菌纯化的热稳定肠毒素（ST）在乳鼠中引起的液体蓄积的影响。我们发现氯丙嗪在体外使ST本身失活，但并不抑制ST在肠道中的活性。