Takeda T, Takeda Y, Miwatani T, Ohtomo N
Infect Immun. 1978 Feb;19(2):752-4. doi: 10.1128/iai.19.2.752-754.1978.
For detection of cholera enterotoxin activity, suckling hamster, mouse, and rat models were compared. It was found that not only suckling mice but also suckling rats and hamsters were sensitive to cholera enterotoxin. Among these models, suckling hamsters were the most sensitive and gave positive results with about 1/100 the cholera toxin seen in suckling mice and rats.
为检测霍乱肠毒素活性，对乳鼠、乳大鼠和乳仓鼠模型进行了比较。结果发现，不仅乳鼠，乳大鼠和乳仓鼠对霍乱肠毒素也敏感。在这些模型中，乳仓鼠最为敏感，其产生阳性结果所需的霍乱毒素量约为乳鼠和乳大鼠的1/100。
