Veksler Ia I, Magomedova K M
Ukr Biokhim Zh (1978). 1981 May-Jun;53(3):7-12.
Acute and chronic alcohol intoxication causes a considerable deamidation of central nervous system proteins which is most pronounced in the spinal cord. There occurs rearrangement in the amide bonds lability and in the ratio of easy-hydrolyzable and strongly bound amide groups. The metabolic response to the single administration of ethanol is disturbed. Alcohol intoxication causes changes in the amount of amide groups in the central nervous system proteins under conditions of physical exercises and fatigue development.
急性和慢性酒精中毒会导致中枢神经系统蛋白质发生大量脱酰胺作用，这在脊髓中最为明显。酰胺键的稳定性以及易水解酰胺基团和强结合酰胺基团的比例会发生重新排列。单次摄入乙醇后的代谢反应受到干扰。在体育锻炼和疲劳产生的情况下，酒精中毒会导致中枢神经系统蛋白质中酰胺基团数量的变化。
