Ho F C, Todd D
Cancer. 1978 Nov;42(5):2450-60. doi: 10.1002/1097-0142(197811)42:5<2450::aid-cncr2820420547>3.0.co;2-z.
Five Chinese patients with malignant histiocytosis are described, the diagnosis being based on microscopic evidence of infiltration of at least three different tissues by noncohesive atypical phagocytic histiocytes, without total obliteration of normal architecture of those tissues. The mean age of the patients was 28 years; all presented with pyrexia (of 2 weeks to 2 1/2 years duration) and all had circulating neoplastic cells. Two patients showed remission with quadruple chemotherapy and one is alive and without symptoms 6 years after onset of his illness.
本文描述了5例中国恶性组织细胞增多症患者，诊断依据是显微镜下可见非黏附性非典型吞噬组织细胞浸润至少三种不同组织，且这些组织的正常结构未完全被破坏。患者的平均年龄为28岁；所有患者均有发热（持续2周至2年半），且外周血中均有肿瘤细胞。2例患者接受四联化疗后病情缓解，1例患者在发病6年后仍存活且无症状。
