正常组织和肿瘤组织中的细胞间糖胺聚糖
Intercellular glycosaminoglycans in normal and neoplastic tissues.
作者信息
Chiarugi V P, Vannucchi S, Cella C, Fibbi G, Del Rosso M, Cappelletti R
出版信息
Cancer Res. 1978 Dec;38(12):4717-21.
PMID:719648
Abstract
Intercellular glycosaminoglycans have been isolated from normal and neoplastic mammalian tissues. They have been characterized by cellulose acetate electrophoresis and by chemical and enzymatic degradation. The electrophoretic pattern of the intercellular glycosaminoglycans is tissue specific. Furthermore, the electrophoretic patterns of all spontaneous neoplasias analyzed differ significantly from patterns obtained from the tissues of origin.
摘要
细胞间糖胺聚糖已从正常和肿瘤性哺乳动物组织中分离出来。它们已通过醋酸纤维素电泳以及化学和酶促降解进行了表征。细胞间糖胺聚糖的电泳图谱具有组织特异性。此外，所有分析的自发性肿瘤的电泳图谱与起源组织的图谱有显著差异。
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