Niederau C M, Potthoff S, Reinauer H
Z Geburtshilfe Perinatol. 1981 Jun;185(3):137-40.
Glycosylated hemoglobins were used for the retrospective assessment of glucose metabolism, for therapy control, and as predictor of the weight of the newborn. Glycosylated hemoglobins were determined with the microcolumn method in 50 pregnant diabetics, in 11 overweight pregnant women, in 11 pregnant women under tocolytic treatment, and in 28 metabolically healthy women. Whereas the levels of glycosylated hemoglobins were found to be reduced in metabolically healthy women, the corresponding levels were increased in tocolytically treated, adipose, and diabetic pregnant women. The HbAI values correlated with the mean values of the daily blood glucose profiles (r = 0.79 - 0.94) and decreased during improvement of the metabolic state. A statistic correlation could not be established between the maternal HbAI and the weight of the newborn as the pregnancy period is shortened by dearrangement of the carbohydrate metabolism.
糖化血红蛋白用于回顾性评估葡萄糖代谢、治疗控制以及作为新生儿体重的预测指标。采用微柱法测定了50例妊娠糖尿病患者、11例超重孕妇、11例接受宫缩抑制剂治疗的孕妇以及28例代谢健康女性的糖化血红蛋白。结果发现，代谢健康女性的糖化血红蛋白水平降低，而接受宫缩抑制剂治疗的孕妇、肥胖孕妇和妊娠糖尿病患者的相应水平升高。HbAI值与每日血糖曲线的平均值相关（r = 0.79 - 0.94），并在代谢状态改善时降低。由于碳水化合物代谢紊乱导致孕期缩短，因此无法在母体HbAI与新生儿体重之间建立统计学相关性。
