Andersson A C, Henningsson S
Acta Endocrinol (Copenh). 1981 Nov;98(3):456-63. doi: 10.1530/acta.0.0980456.
The urinary excretion of the diamines histamine, methylhistamine, putrescine and cadaverine and the polyamines spermidine and spermine was studied in rats which on the 19th day of pregnancy were subjected to various ectomizing operations. In sham-operated rats the urinary excretion of all the amines studied except spermine was highly elevated on the day preceding the sham-operation and on the 3 days studied post-operatively, i.e. sham-operation did not affect the elevated urinary amine excretion during pregnancy. Foetectomy resulted in an abolished increase in the urinary excretion of histamine and methylhistamine while the excretion of putrescine, cadaverine and spermidine was still significantly increased. Removal of both the foetuses and placentae reduced the excretion of putrescine, cadaverine and spermidine towards the level of non-pregnant rats. Combined hysterectomy and ovariectomy did not cause any additional effects to those after removal of the foetuses and the placentae except for cadaverine, the excretion of which was further reduced.
对妊娠第19天接受各种切除手术的大鼠，研究了二胺类物质组胺、甲基组胺、腐胺和尸胺以及多胺类物质亚精胺和精胺的尿排泄情况。在假手术大鼠中，除精胺外，所有研究的胺类物质的尿排泄在假手术前一天及术后研究的3天内均显著升高，即假手术不影响孕期尿胺排泄的升高。胎儿切除术导致组胺和甲基组胺的尿排泄增加消失，而腐胺、尸胺和亚精胺的排泄仍显著增加。去除胎儿和胎盘后，腐胺、尸胺和亚精胺的排泄量降至非妊娠大鼠的水平。子宫切除术和卵巢切除术联合进行，除尸胺排泄进一步减少外，对去除胎儿和胎盘后的影响无任何额外作用。
