Tillman L J
Dermatologica. 1981;163(4):343-7.
The unusual ultrastructure of a metastatic malignant melanoma is discussed. Light microscopy revealed most tumor cells to be nonpigmented, multinucleated giant cells. Electron microscopy demonstrated bizarre, cytoplasmic filaments void of melanin deposition. The internal structure of these filaments exhibited distinct periodicity similar to that seen in normal melanosomes.
本文讨论了转移性恶性黑色素瘤的异常超微结构。光学显微镜显示大多数肿瘤细胞为无色素的多核巨细胞。电子显微镜显示出奇异的、无黑色素沉积的细胞质细丝。这些细丝的内部结构呈现出与正常黑素小体相似的明显周期性。
